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Intranasal Delivery of Neural Stem/Progenitor Cells: A Noninvasive Passage to Target Intracerebral Glioma

Identifieur interne : 001198 ( Main/Exploration ); précédent : 001197; suivant : 001199

Intranasal Delivery of Neural Stem/Progenitor Cells: A Noninvasive Passage to Target Intracerebral Glioma

Auteurs : Matthias Reitz ; Maria Demestre ; Jan Sedlacik [Allemagne] ; Hildegard Meissner ; Jens Fiehler [Allemagne] ; Seung U. Kim [Corée du Sud, Canada] ; Manfred Westphal ; Nils Ole Schmidt

Source :

RBID : PMC:3659670

Abstract

This study investigates the feasibility of intranasal administration of neural stem/progenitor cells (NSPCs) as an alternative, noninvasive, and direct passage for the delivery of stem cells to target intracerebral pathologies such as malignant gliomas. Intranasal administration offers the possibility of multiple treatments potentially using tumor-targeting NSPCs with different therapeutic payloads during the disease course.


Url:
DOI: 10.5966/sctm.2012-0045
PubMed: 23283548
PubMed Central: 3659670


Affiliations:


Links toward previous steps (curation, corpus...)


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